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GO Term :

Identifier  GO:0005852 Name  eukaryotic translation initiation factor 3 complex
Ontology . Name  GO Namespace  cellular_component
Obsolete  false
description  A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
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Gene Ontology

35 Ontology Annotations

10 Parents

2 Synonyms

 

Other

0 Cross References

1 Data Sets

1 Ontology

14 Relations