help  | about  | cite  | software

Gene : FGR Homo sapiens

Name  ? FGR proto-oncogene, Src family tyrosine kinase Cytological Location  1p35.3
Brief Description  FGR proto-oncogene, Src family tyrosine kinase
description  This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • synonyms:
  • SRC2,
  • HGNC:3697,
  • p58-Fgr,
  • p55c-fgr,
  • NM_005248,
  • BC064382,
  • c-src2,
  • uc001bom.4,
  • p55-Fgr,
  • feline Gardner-Rasheed sarcoma viral oncogene homolog,
  • Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog,
  • FGR,
  • p58c-fgr,
  • SRC2,
  • c-fgr,
  • OTTHUMG00000003516,
  • p55c-fgr,
  • v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog,
  • c-fgr
  • identifiers:
  • 2268,
  • ENSG00000000938,
  • FGR

Genome feature

Region: gene ? Length: 23273  
Location: 1:27612289-27635561 reverse strand Cyto location: 1p35.3

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



53 SN Ps

5 Cross References

17 Data Sets

34 Homologues

0 Located Features

90 Rna Seq Results