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Gene : LASP1 Homo sapiens

Name  ? LIM and SH3 protein 1 Cytological Location  17q12
Brief Description  LIM and SH3 protein 1
description  This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012]
  • synonyms:
  • MLN50,
  • uc002hra.3,
  • NM_006148,
  • OTTHUMG00000133182,
  • HGNC:6513,
  • LASP1,
  • MLN50,
  • Lasp-1,
  • Lasp-1
  • identifiers:
  • 3927,
  • ENSG00000002834,
  • LASP1

Genome feature

Region: gene ? Length: 51912  
Location: 17:38869859-38921770 Cyto location: 17q12

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0 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

132 SN Ps

5 Cross References

16 Data Sets

3 Homologues

0 Located Features

90 Rna Seq Results