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Gene : MGST1 Homo sapiens
Name  ? microsomal glutathione S-transferase 1 Cytological Location  12p12.3
Brief Description  microsomal glutathione S-transferase 1
description  The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012]
  • synonyms:
  • MGST-I,
  • uc001rdf.4,
  • MGST-I,
  • MGST,
  • U46494,
  • OTTHUMG00000168816,
  • MGST1,
  • GST12,
  • HGNC:7061,
  • GST12,
  • NM_145791
  • identifiers:
  • 4257,
  • ENSG00000008394,
  • MGST1

Genome feature

Region: gene ? Length: 30048  
Location: 12:16347142-16377189 Cyto location: 12p12.3


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Lists
This Gene is in one list:
PL_BHF_UCL_cardiovascGenes (4103)

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Function

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11 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

11 Pathways

622 SN Ps

5 Cross References

16 Data Sets

8 Homologues

0 Located Features

90 Rna Seq Results





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