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Gene : RNF14 Homo sapiens

Name  ? ring finger protein 14 Cytological Location  5q31.3
Brief Description  ring finger protein 14
description  The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
  • synonyms:
  • NM_004290,
  • HGNC:10058,
  • HFB30,
  • TRIAD2,
  • uc003llz.4,
  • RNF14,
  • OTTHUMG00000129660,
  • HRIHFB2038,
  • TRIAD2,
  • AF060544,
  • ARA54,
  • ARA54,
  • HFB30
  • identifiers:
  • 9604,
  • ENSG00000013561,
  • RNF14

Genome feature

Region: gene ? Length: 23485  
Location: 5:141966807-141990291 Cyto location: 5q31.3


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Disease

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Expression

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2011 SN Ps

5 Cross References

15 Data Sets

13 Homologues

0 Located Features

90 Rna Seq Results