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Gene : BAK1 Homo sapiens

Name  ? BCL2 antagonist/killer 1 Cytological Location  6p21.31
Brief Description  BCL2 antagonist/killer 1
description  The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:949,
  • uc003oes.4,
  • BCL2-antagonist/killer 1,
  • CDN1,
  • BCL2L7,
  • CDN1,
  • BAK1,
  • BAK,
  • BCL2L7,
  • OTTHUMG00000014530,
  • BAK-LIKE,
  • NM_001188,
  • U23765,
  • BAK
  • identifiers:
  • 578,
  • ENSG00000030110,
  • BAK1

Genome feature

Region: gene ? Length: 7751  
Location: 6:33572546-33580296 reverse strand Cyto location: 6p21.31


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Proteins

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SNPs

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Disease

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Homology

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Expression

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2011 SN Ps

5 Cross References

16 Data Sets

10 Homologues

0 Located Features

90 Rna Seq Results