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Gene : DLX3 Homo sapiens

Name  ? distal-less homeobox 3 Cytological Location  17q21.33
Brief Description  distal-less homeobox 3
description  Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AI4,
  • OTTHUMG00000161892,
  • DLX3,
  • NM_005220,
  • distal-less homeo box 3,
  • HGNC:2916,
  • uc002ipy.3,
  • TDO
  • identifiers:
  • 1747,
  • ENSG00000064195,
  • DLX3

Genome feature

Region: gene ? Length: 5220  
Location: 17:49990005-49995224 reverse strand Cyto location: 17q21.33


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Function

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0 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

37 SN Ps

5 Cross References

16 Data Sets

15 Homologues

0 Located Features

90 Rna Seq Results