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Gene : SPA17 Homo sapiens

Name  ? sperm autoantigenic protein 17 Cytological Location  11q24.2
Brief Description  sperm autoantigenic protein 17
description  This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009]
  • synonyms:
  • HGNC:11210,
  • CT22,
  • uc058ird.1,
  • SP17-1,
  • SPA17,
  • AF334735,
  • SP17,
  • SP17,
  • CT22,
  • OTTHUMG00000165927,
  • cancer/testis antigen 22,
  • NM_017425
  • identifiers:
  • 53340,
  • ENSG00000064199,
  • SPA17

Genome feature

Region: gene ? Length: 20951  
Location: 11:124673844-124694794 Cyto location: 11q24.2

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0 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

2011 SN Ps

5 Cross References

16 Data Sets

8 Homologues

0 Located Features

90 Rna Seq Results