help  | about  | cite  | software

Gene : KARS Homo sapiens

Name  ? lysyl-tRNA synthetase Cytological Location  16q23.1
Brief Description  lysyl-tRNA synthetase
description  Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000137609,
  • KARS1,
  • KARS2,
  • KARS2,
  • deafness, autosomal recessive 89,
  • HGNC:6215,
  • lysine tRNA ligase,
  • uc002fer.4,
  • NM_005548,
  • DFNB89,
  • KARS,
  • AF285758,
  • DFNB89,
  • KRS,
  • KARS1
  • identifiers:
  • 3735,
  • ENSG00000065427,
  • KARS

Genome feature

Region: gene ? Length: 19964  
Location: 16:75627724-75647687 reverse strand Cyto location: 16q23.1

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



72 SN Ps

5 Cross References

19 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results