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Gene : PRKCQ Homo sapiens

Name  ? protein kinase C theta Cytological Location  10p15.1
Brief Description  protein kinase C theta
description  Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]
  • synonyms:
  • PRKCQ,
  • HGNC:9410,
  • OTTHUMG00000017623,
  • L07032,
  • protein kinase C, theta,
  • NM_006257,
  • nPKC-theta,
  • PRKCT,
  • uc001ijj.3
  • identifiers:
  • 5588,
  • ENSG00000065675,

Genome feature

Region: gene ? Length: 187609  
Location: 10:6393038-6580646 reverse strand Cyto location: 10p15.1

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50 SN Ps

5 Cross References

16 Data Sets

38 Homologues

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90 Rna Seq Results