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Gene : MTHFD2 Homo sapiens

Name  ? methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Cytological Location  2p13.1
Brief Description  methylenetetrahydrofolate dehydrogenase (NADP dependent) 2, methenyltetrahydrofolate cyclohydrolase
description  This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]
  • synonyms:
  • NM_006636,
  • MTHFD2,
  • OTTHUMG00000129814,
  • X16396,
  • HGNC:7434,
  • uc002skk.4,
  • identifiers:
  • 10797,
  • ENSG00000065911,
  • MTHFD2

Genome feature

Region: gene ? Length: 16736  
Location: 2:74198563-74215298 Cyto location: 2p13.1

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0 Diseases

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122 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

90 Rna Seq Results