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Function
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55 Pathways
- RHO GTPases Activate Formins,
- Signaling by Rho GTPases,
- AXIN mutants destabilize the destruction complex, activating WNT signaling,
- APC truncation mutants have impaired AXIN binding,
- Mitotic Metaphase and Anaphase,
- Signaling by WNT in cancer,
- Degradation of beta-catenin by the destruction complex,
- Signaling by WNT,
- MAPK family signaling cascades,
- RAF activation,
- Separation of Sister Chromatids,
- Mitotic Anaphase,
- Mitotic Prometaphase,
- CTLA4 inhibitory signaling,
- RAF/MAP kinase cascade,
- Immune System,
- S33 mutants of beta-catenin aren't phosphorylated,
- Disassembly of the destruction complex and recruitment of AXIN to the membrane,
- Negative regulation of the PI3K/AKT network,
- T41 mutants of beta-catenin aren't phosphorylated,
- Beta-catenin phosphorylation cascade,
- Mitotic Spindle Checkpoint,
- Wnt signaling pathway,
- TCF dependent signaling in response to WNT,
- Intracellular signaling by second messengers,
- MAPK1/MAPK3 signaling,
- Signal Transduction,
- Hemostasis,
- S45 mutants of beta-catenin aren't phosphorylated,
- Diseases of signal transduction,
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex,
- Misspliced GSK3beta mutants stabilize beta-catenin,
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling,
- mRNA surveillance pathway,
- Adaptive Immune System,
- truncated APC mutants destabilize the destruction complex,
- Amplification of signal from the kinetochores,
- Negative regulation of MAPK pathway,
- Truncations of AMER1 destabilize the destruction complex,
- S37 mutants of beta-catenin aren't phosphorylated,
- Costimulation by the CD28 family,
- Disease,
- Platelet homeostasis,
- Platelet sensitization by LDL,
- AMER1 mutants destabilize the destruction complex,
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal,
- M Phase,
- Cell Cycle,
- Cell Cycle, Mitotic,
- PIP3 activates AKT signaling,
- Oocyte meiosis,
- Cell Cycle Checkpoints,
- Resolution of Sister Chromatid Cohesion,
- AXIN missense mutants destabilize the destruction complex,
- RHO GTPase Effectors
Gene --> GO terms.
Mouse Gene --> Allele [Phenotype]
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Other
55 Pathways
- RHO GTPases Activate Formins,
- Signaling by Rho GTPases,
- AXIN mutants destabilize the destruction complex, activating WNT signaling,
- APC truncation mutants have impaired AXIN binding,
- Mitotic Metaphase and Anaphase,
- Signaling by WNT in cancer,
- Degradation of beta-catenin by the destruction complex,
- Signaling by WNT,
- MAPK family signaling cascades,
- RAF activation,
- Separation of Sister Chromatids,
- Mitotic Anaphase,
- Mitotic Prometaphase,
- CTLA4 inhibitory signaling,
- RAF/MAP kinase cascade,
- Immune System,
- S33 mutants of beta-catenin aren't phosphorylated,
- Disassembly of the destruction complex and recruitment of AXIN to the membrane,
- Negative regulation of the PI3K/AKT network,
- T41 mutants of beta-catenin aren't phosphorylated,
- Beta-catenin phosphorylation cascade,
- Mitotic Spindle Checkpoint,
- Wnt signaling pathway,
- TCF dependent signaling in response to WNT,
- Intracellular signaling by second messengers,
- MAPK1/MAPK3 signaling,
- Signal Transduction,
- Hemostasis,
- S45 mutants of beta-catenin aren't phosphorylated,
- Diseases of signal transduction,
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex,
- Misspliced GSK3beta mutants stabilize beta-catenin,
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling,
- mRNA surveillance pathway,
- Adaptive Immune System,
- truncated APC mutants destabilize the destruction complex,
- Amplification of signal from the kinetochores,
- Negative regulation of MAPK pathway,
- Truncations of AMER1 destabilize the destruction complex,
- S37 mutants of beta-catenin aren't phosphorylated,
- Costimulation by the CD28 family,
- Disease,
- Platelet homeostasis,
- Platelet sensitization by LDL,
- AMER1 mutants destabilize the destruction complex,
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal,
- M Phase,
- Cell Cycle,
- Cell Cycle, Mitotic,
- PIP3 activates AKT signaling,
- Oocyte meiosis,
- Cell Cycle Checkpoints,
- Resolution of Sister Chromatid Cohesion,
- AXIN missense mutants destabilize the destruction complex,
- RHO GTPase Effectors