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Pathway : RNA transport

Identifier  03013 Description  RNA transport from the nucleus to the cytoplasm is  fundamental for gene expression The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes NPCs via mobile export receptors The majority of RNAs, such as tRNAs, rRNAs, and U snRNAs, are transported by specific export receptors, which belong to the karyopherin-beta family proteins A feature of karyopherins is their regulation by the small GTPase Ran However, general mRNA export is mechanistically different Nuclear export of mRNAs is functionally coupled to different steps in gene expression processes, such as transcription, splicing, 3'-end formation and even translation

1 Data Sets

316 Genes

0 Proteins