help  | about  | cite  | software

Gene : RHOA Homo sapiens

Name  ? ras homolog family member A Cytological Location  3p21.31
Brief Description  ras homolog family member A
description  This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
  • synonyms:
  • HGNC:667,
  • uc003cwu.4,
  • ARHA,
  • RhoA,
  • ARH12,
  • ras homolog gene family, member A,
  • BC001360,
  • OTTHUMG00000156838,
  • RHOA,
  • ARHA,
  • NM_001664,
  • RHO12,
  • RHOH12,
  • Rho12,
  • ARH12,
  • RHOH12
  • identifiers:
  • 387,
  • ENSG00000067560,
  • RHOA

Genome feature

Region: gene ? Length: 52962  
Location: 3:49359136-49412097 reverse strand Cyto location: 3p21.31

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

76 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



76 Pathways

784 SN Ps

5 Cross References

18 Data Sets

35 Homologues

0 Located Features

90 Rna Seq Results