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Gene : RHOA Homo sapiens

Name  ? ras homolog family member A Cytological Location  3p21.31
Brief Description  ras homolog family member A
description  This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
  • synonyms:
  • RHOA,
  • HGNC:667,
  • uc003cwu.4,
  • BC001360,
  • RHOH12,
  • RHOH12,
  • ARHA,
  • RhoA,
  • ARH12,
  • Rho12,
  • ARH12,
  • RHO12,
  • NM_001664,
  • OTTHUMG00000156838,
  • ras homolog gene family, member A,
  • ARHA
  • identifiers:
  • 387,
  • ENSG00000067560,
  • RHOA

Genome feature

Region: gene ? Length: 52962  
Location: 3:49359136-49412097 reverse strand Cyto location: 3p21.31


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Function

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76 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

76 Pathways

784 SN Ps

5 Cross References

18 Data Sets

35 Homologues

0 Located Features

90 Rna Seq Results