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Gene : NCK2 Homo sapiens

Name  ? NCK adaptor protein 2 Cytological Location  2q12.2
Brief Description  NCK adaptor protein 2
description  This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NCK2,
  • GRB4,
  • NCKbeta,
  • NCKbeta,
  • HGNC:7665,
  • NM_003581,
  • OTTHUMG00000153116,
  • AF043119,
  • uc002tdg.4
  • identifiers:
  • 8440,
  • ENSG00000071051,
  • NCK2

Genome feature

Region: gene ? Length: 149626  
Location: 2:105744649-105894274 Cyto location: 2q12.2


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

481 SN Ps

5 Cross References

17 Data Sets

10 Homologues

0 Located Features

90 Rna Seq Results