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Gene : FLT3LG Homo sapiens

Name  ? fms related tyrosine kinase 3 ligand Cytological Location  19q13.33
Brief Description  fms related tyrosine kinase 3 ligand
description  Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
  • synonyms:
  • NM_001204502,
  • FLG3L,
  • FLT3L,
  • FL,
  • FLT3LG,
  • uc002pnu.4,
  • OTTHUMG00000186490,
  • fms-related tyrosine kinase 3 ligand,
  • U04806,
  • HGNC:3766
  • identifiers:
  • 2323,
  • ENSG00000090554,
  • FLT3LG

Genome feature

Region: gene ? Length: 12866  
Location: 19:49474172-49487037 Cyto location: 19q13.33


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> GO terms.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

64 SN Ps

5 Cross References

15 Data Sets

3 Homologues

0 Located Features

90 Rna Seq Results