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Gene : SUN2 Homo sapiens

Name  ? Sad1 and UNC84 domain containing 2 Cytological Location  22q13.1
Brief Description  Sad1 and UNC84 domain containing 2
description  SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
  • synonyms:
  • HGNC:14210,
  • AF202723,
  • SUN2,
  • NM_001199579,
  • unc-84 homolog B (C. elegans),
  • uc010gxr.3,
  • UNC84B,
  • OTTHUMG00000151031,
  • UNC84B
  • identifiers:
  • 25777,
  • ENSG00000100242,
  • SUN2

Genome feature

Region: gene ? Length: 21306  
Location: 22:38734714-38756019 reverse strand Cyto location: 22q13.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

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Mouse Gene --> Allele [Phenotype]


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885 SN Ps

5 Cross References

17 Data Sets

12 Homologues

0 Located Features

90 Rna Seq Results