help  | about  | cite  | software

Gene : PPP2R1A Homo sapiens

Name  ? protein phosphatase 2 scaffold subunit Aalpha Cytological Location  19q13.41
Brief Description  protein phosphatase 2 scaffold subunit Aalpha
description  This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
  • synonyms:
  • PP2A-Aalpha,
  • uc002pyp.4,
  • MRD36,
  • PP2AA,
  • PR65A,
  • PP2AA,
  • protein phosphatase 2, 65kDa regulatory subunit A,
  • OTTHUMG00000137367,
  • NM_014225,
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform,
  • protein phosphatase 2A, regulatory subunit A, alpha isoform,
  • protein phosphatase 2A structural subunit A, alpha isoform,
  • PPP2R1A,
  • PP2A-Aalpha,
  • HGNC:9302,
  • PR65A
  • identifiers:
  • 5518,
  • ENSG00000105568,
  • PPP2R1A

Genome feature

Region: gene ? Length: 36624  
Location: 19:52189802-52226425 Cyto location: 19q13.41

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



697 SN Ps

5 Cross References

18 Data Sets

10 Homologues

0 Located Features

90 Rna Seq Results