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Gene : IL2 Homo sapiens

Name  ? interleukin 2 Cytological Location  4q27
Brief Description  interleukin 2
description  The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
  • synonyms:
  • U25676,
  • T cell growth factor,
  • IL-2,
  • IL2,
  • uc003ier.4,
  • TCGF,
  • HGNC:6001,
  • lymphokine,
  • OTTHUMG00000133075,
  • IL-2,
  • TCGF,
  • NM_000586
  • identifiers:
  • 3558,
  • ENSG00000109471,
  • IL2

Genome feature

Region: gene ? Length: 7017  
Location: 4:122449479-122456495 reverse strand Cyto location: 4q27


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

1 SN Ps

5 Cross References

15 Data Sets

0 Homologues

0 Located Features

90 Rna Seq Results