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Gene : PLAGL1 Homo sapiens

Name  ? PLAG1 like zinc finger 1 Cytological Location  6q24.2
Brief Description  PLAG1 like zinc finger 1
description  This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015]
  • synonyms:
  • OTTHUMG00000015738,
  • U81992,
  • pleiomorphic adenoma gene-like 1,
  • ZAC,
  • ZAC,
  • PLAGL1,
  • ZAC1,
  • uc003qkj.5,
  • NM_001080951,
  • HGNC:9046,
  • LOT1,
  • LOT1
  • identifiers:
  • 5325,
  • ENSG00000118495,
  • PLAGL1

Genome feature

Region: gene ? Length: 124300  
Location: 6:143940300-144064599 reverse strand Cyto location: 6q24.2


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

107 SN Ps

5 Cross References

16 Data Sets

26 Homologues

0 Located Features

90 Rna Seq Results