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Gene : ABCC11 Homo sapiens

Name  ? ATP binding cassette subfamily C member 11 Cytological Location  16q12.1
Brief Description  ATP binding cassette subfamily C member 11
description  The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • EWWD,
  • uc059txd.1,
  • MRP8,
  • ABCC11,
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 11,
  • HGNC:14639,
  • OTTHUMG00000133146,
  • AF367202,
  • WW,
  • NM_032583,
  • MRP8
  • identifiers:
  • 85320,
  • ENSG00000121270,
  • ABCC11

Genome feature

Region: gene ? Length: 85132  
Location: 16:48164842-48249973 reverse strand Cyto location: 16q12.1


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

761 SN Ps

5 Cross References

17 Data Sets

20 Homologues

0 Located Features

90 Rna Seq Results