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Gene : POR Homo sapiens

Name  ? cytochrome p450 oxidoreductase Cytological Location  7q11.23
Brief Description  cytochrome p450 oxidoreductase
description  This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CYPOR,
  • FLJ26468,
  • CPR,
  • uc003udy.4,
  • P450R,
  • OTTHUMG00000130413,
  • AF258341,
  • CYPOR,
  • NADPH--hemoprotein reductase,
  • HGNC:9208,
  • P450 (cytochrome) oxidoreductase,
  • NM_000941,
  • POR
  • identifiers:
  • 5447,
  • ENSG00000127948,
  • POR

Genome feature

Region: gene ? Length: 71754  
Location: 7:75915102-75986855 Cyto location: 7q11.23


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Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

2011 SN Ps

5 Cross References

19 Data Sets

12 Homologues

0 Located Features

90 Rna Seq Results