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Gene : NUMB Homo sapiens

Name  ? NUMB endocytic adaptor protein Cytological Location  14q24.2-q24.3
Brief Description  NUMB, endocytic adaptor protein
description  The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
  • synonyms:
  • C14orf41,
  • c14_5527,
  • HGNC:8060,
  • S171,
  • numb (Drosophila) homolog,
  • OTTHUMG00000171436,
  • NM_001005743,
  • numb homolog (Drosophila),
  • uc001xny.2,
  • NUMB,
  • C14orf41,
  • L40393,
  • chromosome 14 open reading frame 41
  • identifiers:
  • 8650,
  • ENSG00000133961,
  • NUMB

Genome feature

Region: gene ? Length: 183371  
Location: 14:73275210-73458580 reverse strand Cyto location: 14q24.2-q24.3

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0 Diseases

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709 SN Ps

5 Cross References

17 Data Sets

15 Homologues

0 Located Features

90 Rna Seq Results