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Gene : TEC Homo sapiens

Name  ? tec protein tyrosine kinase Cytological Location  4p12-p11
Brief Description  tec protein tyrosine kinase
description  The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008]
  • synonyms:
  • PSCTK4,
  • OTTHUMG00000128623,
  • D29767,
  • NM_003215,
  • uc003gxz.4,
  • PSCTK4,
  • TEC,
  • HGNC:11719
  • identifiers:
  • 7006,
  • ENSG00000135605,
  • TEC

Genome feature

Region: gene ? Length: 134082  
Location: 4:48135783-48269864 reverse strand Cyto location: 4p12-p11


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Function

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Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

693 SN Ps

4 Cross References

16 Data Sets

34 Homologues

0 Located Features

90 Rna Seq Results