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Gene : TANK Homo sapiens

Name  ? TRAF family member associated NFKB activator Cytological Location  2q24.2
Brief Description  TRAF family member associated NFKB activator
description  The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
  • synonyms:
  • OTTHUMG00000132037,
  • uc002ubr.3,
  • TANK,
  • I-TRAF,
  • TRAF family member-associated NFKB activator,
  • NM_133484,
  • ITRAF,
  • HGNC:11562,
  • TRAF2,
  • U59863,
  • I-TRAF,
  • TRAF2
  • identifiers:
  • 10010,
  • ENSG00000136560,
  • TANK

Genome feature

Region: gene ? Length: 99222  
Location: 2:161136955-161236176 Cyto location: 2q24.2


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133 SN Ps

5 Cross References

17 Data Sets

3 Homologues

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90 Rna Seq Results