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Gene : LGR5 Homo sapiens

Name  ? leucine rich repeat containing G protein-coupled receptor 5 Cytological Location  12q21.1
Brief Description  leucine rich repeat containing G protein-coupled receptor 5
description  The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
  • synonyms:
  • LGR5,
  • HG38,
  • G protein-coupled receptor 49,
  • FEX,
  • AF062006,
  • GPR67,
  • HGNC:4504,
  • HG38,
  • OTTHUMG00000169543,
  • GPR67,
  • GPR49,
  • uc001swl.5,
  • GPR49,
  • FEX,
  • NM_003667,
  • GRP49
  • identifiers:
  • 8549,
  • ENSG00000139292,
  • LGR5

Genome feature

Region: gene ? Length: 146541  
Location: 12:71439770-71586310 Cyto location: 12q21.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Mouse Gene --> Allele [Phenotype]


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253 SN Ps

5 Cross References

16 Data Sets

10 Homologues

0 Located Features

90 Rna Seq Results