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Gene : CDH13 Homo sapiens

Name  ? cadherin 13 Cytological Location  16q23.3
Brief Description  cadherin 13
description  This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011]
  • synonyms:
  • uc010vns.3,
  • OTTHUMG00000176635,
  • CDHH,
  • P105,
  • NM_001257,
  • CDH13,
  • HGNC:1753,
  • U59288,
  • T-cadherin,
  • H-cadherin (heart),
  • CDHH
  • identifiers:
  • 1012,
  • ENSG00000140945,
  • CDH13

Genome feature

Region: gene ? Length: 1169817  
Location: 16:82626794-83796610 Cyto location: 16q23.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

424 SN Ps

5 Cross References

16 Data Sets

27 Homologues

0 Located Features

90 Rna Seq Results