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Gene : CDC42BPA Homo sapiens

Name  ? CDC42 binding protein kinase alpha Cytological Location  1q42.13
Brief Description  CDC42 binding protein kinase alpha
description  The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018]
  • synonyms:
  • HGNC:1737,
  • PK428,
  • MRCK,
  • MRCKA,
  • MRCKA,
  • myotonic dystrophy kinase-related Cdc42-binding kinase,
  • PK428,
  • NM_014826,
  • uc001hqr.4,
  • OTTHUMG00000037618,
  • U59305,
  • MRCK,
  • KIAA0451,
  • FLJ23347,
  • CDC42-binding protein kinase alpha (DMPK-like),
  • CDC42BPA
  • identifiers:
  • 8476,
  • ENSG00000143776,
  • CDC42BPA

Genome feature

Region: gene ? Length: 328638  
Location: 1:226989865-227318502 reverse strand Cyto location: 1q42.13


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Disease

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Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

0 Pathways

2011 SN Ps

5 Cross References

17 Data Sets

11 Homologues

1 Located Features

90 Rna Seq Results