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Gene : HS2ST1 Homo sapiens

Name  ? heparan sulfate 2-O-sulfotransferase 1 Cytological Location  1p22.3
Brief Description  heparan sulfate 2-O-sulfotransferase 1
description  Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008]
  • synonyms:
  • HS2ST1,
  • HGNC:5193,
  • OTTHUMG00000010255,
  • KIAA0448,
  • uc010osk.3,
  • dJ604K5.2,
  • AB007917,
  • NM_012262
  • identifiers:
  • 9653,
  • ENSG00000153936,
  • HS2ST1

Genome feature

Region: gene ? Length: 195347  
Location: 1:86914652-87109998 Cyto location: 1p22.3

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0 Diseases

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2011 SN Ps

5 Cross References

16 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results