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Gene : BUB1B Homo sapiens

Name  ? BUB1 mitotic checkpoint serine/threonine kinase B Cytological Location  15q15.1
Brief Description  BUB1 mitotic checkpoint serine/threonine kinase B
description  This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
  • synonyms:
  • MAD3L,
  • BUBR1,
  • HGNC:1149,
  • BUB1B,
  • budding uninhibited by benzimidazoles 1 (yeast homolog), beta,
  • NM_001211,
  • OTTHUMG00000129877,
  • hBUBR1,
  • Bub1A,
  • Bub1A,
  • AF107297,
  • budding uninhibited by benzimidazoles 1 homolog beta (yeast),
  • SSK1,
  • MVA1,
  • SSK1,
  • MAD3L,
  • uc001zkx.5,
  • BUB1beta,
  • BUBR1
  • identifiers:
  • 701,
  • ENSG00000156970,
  • BUB1B

Genome feature

Region: gene ? Length: 60128  
Location: 15:40161009-40221136 Cyto location: 15q15.1

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3 Diseases

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160 SN Ps

5 Cross References

18 Data Sets

11 Homologues

1 Located Features

90 Rna Seq Results