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Gene : APPL1 Homo sapiens

Name  ? adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Cytological Location  3p14.3
Brief Description  adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
description  The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
  • synonyms:
  • APPL,
  • uc003dio.4,
  • HGNC:24035,
  • APPL1,
  • NM_012096,
  • OTTHUMG00000133756,
  • DCC-interacting protein 13-alpha,
  • APPL,
  • MODY14,
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1,
  • DIP13alpha,
  • AB037849
  • identifiers:
  • 26060,
  • ENSG00000157500,
  • APPL1

Genome feature

Region: gene ? Length: 45735  
Location: 3:57227737-57273471 Cyto location: 3p14.3


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Proteins

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SNPs

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Disease

1 Diseases

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556 SN Ps

5 Cross References

18 Data Sets

4 Homologues

0 Located Features

90 Rna Seq Results