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Gene : MST1R Homo sapiens

Name  ? macrophage stimulating 1 receptor Cytological Location  3p21.31
Brief Description  macrophage stimulating 1 receptor
description  This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]
  • synonyms:
  • PTK8,
  • CDw136,
  • PTK8,
  • X70040,
  • RON,
  • NM_001244937,
  • CD136,
  • CDw136,
  • uc003cxy.5,
  • PTK8 protein tyrosine kinase 8,
  • RON,
  • HGNC:7381,
  • CD136,
  • c-met-related tyrosine kinase,
  • MST1R,
  • OTTHUMG00000156709,
  • NPCA3
  • identifiers:
  • 4486,
  • ENSG00000164078,
  • MST1R

Genome feature

Region: gene ? Length: 17167  
Location: 3:49886471-49903637 reverse strand Cyto location: 3p21.31


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Disease

1 Diseases

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2011 SN Ps

5 Cross References

18 Data Sets

59 Homologues

0 Located Features

90 Rna Seq Results