help  | about  | cite  | software

Gene : CEL Homo sapiens

Name  ? carboxyl ester lipase Cytological Location  9q34.13
Brief Description  carboxyl ester lipase
description  The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc010naa.3,
  • FAP,
  • M54994,
  • MODY8,
  • BSDL,
  • CEase,
  • BAL,
  • HGNC:1848,
  • CELL,
  • BSSL,
  • bile salt-stimulated lipase,
  • FAPP,
  • OTTHUMG00000020855,
  • BSSL,
  • NM_001807,
  • MODY8,
  • CEL,
  • LIPA
  • identifiers:
  • 1056,
  • ENSG00000170835,
  • CEL

Genome feature

Region: gene ? Length: 9886  
Location: 9:133061978-133071863 Cyto location: 9q34.13


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

78 SN Ps

5 Cross References

19 Data Sets

17 Homologues

0 Located Features

90 Rna Seq Results