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Gene : RAD51B Homo sapiens

Name  ? RAD51 paralog B Cytological Location  14q24.1
Brief Description  RAD51 paralog B
description  The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016]
  • synonyms:
  • RAD51-like 1 (S. cerevisiae),
  • OTTHUMG00000157530,
  • RAD51 homolog B (S. cerevisiae),
  • R51H2,
  • NM_001321809,
  • RAD51L1,
  • HGNC:9822,
  • RAD51L1,
  • REC2,
  • hREC2,
  • REC2,
  • R51H2,
  • uc001xkd.4,
  • RAD51B,
  • RAD51 (S. cerevisiae)-like 1,
  • U84138
  • identifiers:
  • 5890,
  • ENSG00000182185,
  • RAD51B

Genome feature

Region: gene ? Length: 863340  
Location: 14:67819779-68683118 Cyto location: 14q24.1


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

39 SN Ps

5 Cross References

18 Data Sets

2 Homologues

0 Located Features

90 Rna Seq Results