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Gene : ARAP1 Homo sapiens

Name  ? ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 Cytological Location  11q13.4
Brief Description  ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
description  The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
  • synonyms:
  • centaurin, delta 2,
  • OTTHUMG00000157102,
  • CENTD2,
  • ARAP1,
  • AF411983,
  • HGNC:16925,
  • CENTD2,
  • NM_001040118,
  • uc001osu.4
  • identifiers:
  • 116985,
  • ENSG00000186635,
  • ARAP1

Genome feature

Region: gene ? Length: 67321  
Location: 11:72685069-72752389 reverse strand Cyto location: 11q13.4


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Disease

0 Diseases

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Expression

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Other

896 SN Ps

5 Cross References

17 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results