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Gene : RELN Homo sapiens

Name  ? reelin Cytological Location  7q22.1
Brief Description  reelin
description  This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc010liz.3,
  • OTTHUMG00000157247,
  • PRO1598,
  • RL,
  • HGNC:9957,
  • LIS2,
  • PRO1598,
  • ETL7,
  • NM_005045,
  • RELN,
  • RL
  • identifiers:
  • 5649,
  • ENSG00000189056,
  • RELN

Genome feature

Region: gene ? Length: 517733  
Location: 7:103471784-103989516 reverse strand Cyto location: 7q22.1


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

374 SN Ps

5 Cross References

18 Data Sets

2 Homologues

0 Located Features

90 Rna Seq Results