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Gene : PDLIM7 Homo sapiens

Name  ? PDZ and LIM domain 7 Cytological Location  5q35.3
Brief Description  PDZ and LIM domain 7
description  The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:22958,
  • BC001093,
  • PDZ and LIM domain 7 (enigma),
  • PDLIM7,
  • NM_005451,
  • LMP1,
  • uc003mhc.3,
  • ENIGMA,
  • LMP3,
  • OTTHUMG00000130853
  • identifiers:
  • 9260,
  • ENSG00000196923,
  • PDLIM7

Genome feature

Region: gene ? Length: 14212  
Location: 5:177483394-177497605 reverse strand Cyto location: 5q35.3


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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

222 SN Ps

5 Cross References

15 Data Sets

16 Homologues

0 Located Features

90 Rna Seq Results