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Gene : PCDHA7 Homo sapiens

Name  ? protocadherin alpha 7 Cytological Location  5q31.3
Brief Description  protocadherin alpha 7
description  This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AF152485,
  • PCDH-ALPHA7,
  • CNRN4,
  • CRNR4,
  • CNRS4,
  • CRNR4,
  • uc003lhq.2,
  • CNRS4,
  • KIAA0345-like 7,
  • CNR4,
  • OTTHUMG00000163371,
  • CNR4,
  • NM_018910,
  • ortholog to mouse CNR4,
  • HGNC:8673,
  • PCDHA7
  • identifiers:
  • 56141,
  • ENSG00000204963,
  • PCDHA7

Genome feature

Region: gene ? Length: 177961  
Location: 5:140834384-141012344 Cyto location: 5q31.3


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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Gene --> GO terms.

 

Other

0 Pathways

2011 SN Ps

5 Cross References

13 Data Sets

73 Homologues

0 Located Features

90 Rna Seq Results