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Gene : NME1 Homo sapiens

Name  ? NME/NM23 nucleoside diphosphate kinase 1 Cytological Location  17q21.33
Brief Description  NME/NM23 nucleoside diphosphate kinase 1
description  This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000137474,
  • NME1,
  • NDKA,
  • NBS,
  • NM_000269,
  • X17620,
  • NM23,
  • NDPKA,
  • AL360191,
  • non-metastatic cells 1, protein (NM23A) expressed in,
  • GAAD,
  • NM23-H1,
  • NDPKA,
  • uc002iti.3,
  • NM23-H1,
  • NM23,
  • NB,
  • HGNC:7849,
  • AWD,
  • NDPK-A
  • identifiers:
  • 4830,
  • ENSG00000239672,
  • NME1

Genome feature

Region: gene ? Length: 8531  
Location: 17:51153559-51162089 Cyto location: 17q21.33


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

2011 SN Ps

5 Cross References

17 Data Sets

13 Homologues

0 Located Features

90 Rna Seq Results