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Gene : MRPL45 Homo sapiens

Name  ? mitochondrial ribosomal protein L45 Cytological Location  17q12
Brief Description  mitochondrial ribosomal protein L45
description  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q. [provided by RefSeq, May 2013]
  • synonyms:
  • MRP-L45,
  • BC006235,
  • L45mt,
  • NM_032351,
  • MRPL45,
  • OTTHUMG00000188489,
  • uc032gkt.2,
  • MGC11321,
  • HGNC:16651
  • identifiers:
  • 84311,
  • ENSG00000278845,
  • MRPL45

Genome feature

Region: gene ? Length: 26196  
Location: 17:38297023-38323218 Cyto location: 17q12


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

0 SN Ps

5 Cross References

11 Data Sets

5 Homologues

0 Located Features

37 Rna Seq Results