help  | about  | cite  | software

Gene : PDCD6 Homo sapiens

Name  ? programmed cell death 6 Cytological Location  5p15.33
Brief Description  programmed cell death 6
description  This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012]
  • synonyms:
  • NM_013232,
  • PDCD6,
  • HGNC:8765,
  • PEF1B,
  • PEF1B,
  • apoptosis-linked gene-2,
  • uc003jat.1,
  • ALG-2,
  • ALG-2,
  • ALG2,
  • OTTHUMG00000090283,
  • AF035606
  • identifiers:
  • 10016,
  • ENSG00000249915,
  • PDCD6

Genome feature

Region: gene ? Length: 43354  
Location: 5:271621-314974 Cyto location: 5p15.33


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

2011 SN Ps

5 Cross References

14 Data Sets

5 Homologues

0 Located Features

90 Rna Seq Results