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Gene : PDCD6 Homo sapiens

Name  ? programmed cell death 6 Cytological Location  5p15.33
Brief Description  programmed cell death 6
description  This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012]
  • synonyms:
  • NM_013232,
  • PDCD6,
  • HGNC:8765,
  • PEF1B,
  • PEF1B,
  • apoptosis-linked gene-2,
  • uc003jat.1,
  • ALG-2,
  • ALG-2,
  • ALG2,
  • OTTHUMG00000090283,
  • AF035606
  • identifiers:
  • 10016,
  • ENSG00000249915,
  • PDCD6

Genome feature

Region: gene ? Length: 43354  
Location: 5:271621-314974 Cyto location: 5p15.33

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0 Pathways

Gene --> GO terms.

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


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Gene Ontology

Gene --> GO terms.



0 Pathways

2011 SN Ps

5 Cross References

14 Data Sets

5 Homologues

0 Located Features

90 Rna Seq Results