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Gene : CST8 Homo sapiens

Name  ? cystatin 8 Cytological Location  20p11.21
Brief Description  cystatin 8
description  The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The encoded protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  • synonyms:
  • OTTHUMG00000032071,
  • CTES5,
  • CRES,
  • CST8,
  • NM_001281730,
  • AF059244,
  • CRES,
  • cystatin 8 (cystatin-related epididymal specific),
  • HGNC:2480,
  • uc002wth.3,
  • CTES5
  • identifiers:
  • 10047,
  • ENSG00000125815,
  • CST8

Genome feature

Region: gene ? Length: 16048  
Location: 20:23491077-23507124 Cyto location: 20p11.21


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Function

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0 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

167 SN Ps

4 Cross References

12 Data Sets

2 Homologues

0 Located Features

90 Rna Seq Results