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Gene : DNM1L Homo sapiens

Name  ? dynamin 1 like Cytological Location  12p11.21
Brief Description  dynamin 1 like
description  This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
  • synonyms:
  • DVLP,
  • DLP1,
  • NM_012062,
  • DVLP,
  • OPA5,
  • EMPF,
  • VPS1,
  • DRP1,
  • HGNC:2973,
  • DYMPLE,
  • DNM1L,
  • EMPF1,
  • OTTHUMG00000169451,
  • HDYNIV,
  • HDYNIV,
  • uc001rlf.4,
  • DRP1,
  • AF000430,
  • DYMPLE
  • identifiers:
  • 10059,
  • ENSG00000087470,
  • DNM1L

Genome feature

Region: gene ? Length: 66451  
Location: 12:32679200-32745650 Cyto location: 12p11.21


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Disease

2 Diseases

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Expression

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2011 SN Ps

5 Cross References

19 Data Sets

14 Homologues

0 Located Features

90 Rna Seq Results