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Gene : ADAM8 Homo sapiens

Name  ? ADAM metallopeptidase domain 8 Cytological Location  10q26.3
Brief Description  ADAM metallopeptidase domain 8
description  This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]
  • synonyms:
  • MS2,
  • NM_001109,
  • OTTHUMG00000019309,
  • CD156,
  • D26579,
  • MS2,
  • a disintegrin and metalloproteinase domain 8,
  • HGNC:215,
  • uc021qbe.2,
  • CD156a,
  • CD156,
  • CD156a,
  • ADAM8
  • identifiers:
  • 101,
  • ENSG00000151651,
  • ADAM8

Genome feature

Region: gene ? Length: 14488  
Location: 10:133262416-133276903 reverse strand Cyto location: 10q26.3


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

83 SN Ps

5 Cross References

15 Data Sets

29 Homologues

0 Located Features

90 Rna Seq Results