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Gene : CDK8 Homo sapiens

Name  ? cyclin dependent kinase 8 Cytological Location  13q12.13
Brief Description  cyclin dependent kinase 8
description  This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
  • synonyms:
  • NM_001260,
  • OTTHUMG00000016617,
  • K35,
  • K35,
  • CDK8,
  • uc001uqr.2,
  • HGNC:1779,
  • cyclin-dependent kinase 8,
  • X85753
  • identifiers:
  • 1024,
  • ENSG00000132964,
  • CDK8

Genome feature

Region: gene ? Length: 151135  
Location: 13:26254104-26405238 Cyto location: 13q12.13


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Disease

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419 SN Ps

5 Cross References

15 Data Sets

32 Homologues

0 Located Features

90 Rna Seq Results