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Gene : RTN3 Homo sapiens

Name  ? reticulon 3 Cytological Location  11q13.1
Brief Description  reticulon 3
description  This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]
  • synonyms:
  • ASYIP,
  • AF059524,
  • uc001nxo.4,
  • NSPL2,
  • NSPL2,
  • NSPLII,
  • OTTHUMG00000168056,
  • ASYIP,
  • HAP,
  • NM_006054,
  • HGNC:10469,
  • neuroendocrine-specific protein-like 2,
  • isoforme III,
  • homolog of ASY protein,
  • RTN3-A1,
  • HAP,
  • NSP-like protein II,
  • ASY interacting protein,
  • NSPLII,
  • RTN3-A1,
  • RTN3
  • identifiers:
  • 10313,
  • ENSG00000133318,
  • RTN3

Genome feature

Region: gene ? Length: 78577  
Location: 11:63681315-63759891 Cyto location: 11q13.1


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474 SN Ps

5 Cross References

15 Data Sets

9 Homologues

0 Located Features

90 Rna Seq Results