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Gene : BPNT1 Homo sapiens

Name  ? 3'(2'), 5'-bisphosphate nucleotidase 1 Cytological Location  1q41
Brief Description  3'(2'), 5'-bisphosphate nucleotidase 1
description  BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_006085,
  • PIP,
  • HEL20,
  • BPNT1,
  • AF125042,
  • OTTHUMG00000037435,
  • HGNC:1096,
  • uc057png.1
  • identifiers:
  • 10380,
  • ENSG00000162813,
  • BPNT1

Genome feature

Region: gene ? Length: 32435  
Location: 1:220057482-220089916 reverse strand Cyto location: 1q41


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Disease

0 Diseases

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71 SN Ps

5 Cross References

15 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results