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Gene : ANAPC10 Homo sapiens

Name  ? anaphase promoting complex subunit 10 Cytological Location  4q31.21
Brief Description  anaphase promoting complex subunit 10
description  ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).[supplied by OMIM, Feb 2011]
  • synonyms:
  • HGNC:24077,
  • ANAPC10,
  • DOC1,
  • uc031shp.1,
  • DKFZP564L0562,
  • DOC1,
  • APC10,
  • NM_014885,
  • AF132794,
  • APC10,
  • OTTHUMG00000161477
  • identifiers:
  • 10393,
  • ENSG00000164162,
  • ANAPC10

Genome feature

Region: gene ? Length: 131425  
Location: 4:144967117-145098541 reverse strand Cyto location: 4q31.21


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Function

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41 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

41 Pathways

9 SN Ps

5 Cross References

17 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results