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Gene : UBE2E3 Homo sapiens

Name  ? ubiquitin conjugating enzyme E2 E3 Cytological Location  2q31.3
Brief Description  ubiquitin conjugating enzyme E2 E3
description  The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013]
  • synonyms:
  • ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5),
  • AB017644,
  • UbcH9,
  • OTTHUMG00000132585,
  • NM_006357,
  • uc032oln.2,
  • ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast),
  • ubiquitin-conjugating enzyme E2E 3,
  • HGNC:12479,
  • UBE2E3,
  • UBCH9,
  • UbcM2
  • identifiers:
  • 10477,
  • ENSG00000170035,
  • UBE2E3

Genome feature

Region: gene ? Length: 83043  
Location: 2:180980385-181063427 Cyto location: 2q31.3


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Function

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Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

2011 SN Ps

5 Cross References

16 Data Sets

35 Homologues

0 Located Features

90 Rna Seq Results