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Gene : UBE2E3 Homo sapiens

Name  ? ubiquitin conjugating enzyme E2 E3 Cytological Location  2q31.3
Brief Description  ubiquitin conjugating enzyme E2 E3
description  The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013]
  • synonyms:
  • ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5),
  • AB017644,
  • UbcH9,
  • OTTHUMG00000132585,
  • NM_006357,
  • uc032oln.2,
  • ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast),
  • ubiquitin-conjugating enzyme E2E 3,
  • HGNC:12479,
  • UBE2E3,
  • UBCH9,
  • UbcM2
  • identifiers:
  • 10477,
  • ENSG00000170035,
  • UBE2E3

Genome feature

Region: gene ? Length: 83043  
Location: 2:180980385-181063427 Cyto location: 2q31.3

Uni Prot Comments Displayer

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Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]


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Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



2011 SN Ps

5 Cross References

16 Data Sets

35 Homologues

0 Located Features

90 Rna Seq Results