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Gene : APPBP2 Homo sapiens

Name  ? amyloid beta precursor protein binding protein 2 Cytological Location  17q23.2
Brief Description  amyloid beta precursor protein binding protein 2
description  The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  • synonyms:
  • KIAA0228,
  • APP-BP2,
  • PAT1,
  • HGNC:622,
  • protein interacting with APP tail 1,
  • amyloid beta precursor protein (cytoplasmic tail)-binding protein 2,
  • HS.84084,
  • amyloid beta precursor protein (cytoplasmic tail) binding protein 2,
  • NM_006380,
  • PAT1,
  • AF017782,
  • APPBP2,
  • OTTHUMG00000180048,
  • Hs.84084,
  • uc002iys.3
  • identifiers:
  • 10513,
  • ENSG00000062725,
  • APPBP2

Genome feature

Region: gene ? Length: 83092  
Location: 17:60443149-60526240 reverse strand Cyto location: 17q23.2


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

43 SN Ps

5 Cross References

14 Data Sets

4 Homologues

0 Located Features

90 Rna Seq Results